3DYH
T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-721
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004161 | molecular_function | dimethylallyltranstransferase activity |
A | 0004337 | molecular_function | geranyltranstransferase activity |
A | 0004659 | molecular_function | prenyltransferase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0008299 | biological_process | isoprenoid biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
A | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0004161 | molecular_function | dimethylallyltranstransferase activity |
B | 0004337 | molecular_function | geranyltranstransferase activity |
B | 0004659 | molecular_function | prenyltransferase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0008299 | biological_process | isoprenoid biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
B | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG A 3002 |
Chain | Residue |
A | ASP103 |
A | ASP107 |
A | HOH3022 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG A 3003 |
Chain | Residue |
A | ASP255 |
A | HOH3005 |
A | HOH3026 |
A | HOH3048 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG A 3004 |
Chain | Residue |
A | HOH3006 |
A | HOH3017 |
A | HOH3102 |
A | ASP103 |
A | ASP107 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG B 4002 |
Chain | Residue |
B | ASP103 |
B | ASP107 |
B | HOH4006 |
B | HOH4008 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG B 4003 |
Chain | Residue |
B | ASP255 |
B | HOH4039 |
B | HOH4041 |
B | HOH4179 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B 4004 |
Chain | Residue |
B | ASP103 |
B | ASP107 |
B | HOH4020 |
B | HOH4021 |
B | HOH4117 |
site_id | AC7 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE 721 A 3001 |
Chain | Residue |
A | TYR99 |
A | ASP103 |
A | ASP107 |
A | ARG112 |
A | THR168 |
A | GLN172 |
A | LYS212 |
A | THR213 |
A | ASP255 |
A | LYS269 |
A | HOH3005 |
A | HOH3006 |
A | HOH3017 |
A | HOH3022 |
A | HOH3024 |
A | HOH3026 |
A | HOH3047 |
A | HOH3048 |
B | ASN131 |
B | LEU134 |
site_id | AC8 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE 721 B 4001 |
Chain | Residue |
A | ASN131 |
A | LEU134 |
B | TYR99 |
B | ASP103 |
B | ASP107 |
B | ARG112 |
B | THR168 |
B | GLN172 |
B | LYS212 |
B | THR213 |
B | ASP255 |
B | LYS269 |
B | HOH4006 |
B | HOH4008 |
B | HOH4020 |
B | HOH4021 |
B | HOH4032 |
B | HOH4041 |
B | HOH4044 |
B | HOH4179 |
Functional Information from PROSITE/UniProt
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1fps |
Chain | Residue | Details |
A | PHE251 | |
A | ARG112 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1fps |
Chain | Residue | Details |
B | PHE251 | |
B | ARG112 |