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3DY8

Human Phosphodiesterase 9 in complex with product 5'-GMP (E+P complex)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
human phosphodiesterase 9polymer32938862.92UniProt (O76083)
Pfam (PF00233)
Homo sapiens (Human)
2C, F
(A, B)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
3D, G
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E
(A)
GUANOSINE-5'-MONOPHOSPHATEnon-polymer363.21Chemie (5GP)
5H
(B)
3-ISOBUTYL-1-METHYLXANTHINEnon-polymer222.21Chemie (IBM)
6I
(B)
FORMIC ACIDnon-polymer46.01Chemie (FMT)
7J, K
(A, B)
waterwater18.0478Chemie (HOH)
Sequence modifications
A, B: 182 - 506 (UniProt: O76083)
PDBExternal DatabaseDetails
Gly 178-expression tag
Ser 179-expression tag
His 180-expression tag
Met 181-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight77725.9
Non-Polymers*Number of molecules7
Total formula weight790.0
All*Total formula weight78515.8
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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