3DS6
P38 complex with a phthalazine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Mitogen-activated protein kinase 14 | polymer | 366 | 41998.9 | 4 | UniProt (Q16539) Pfam (PF00069) In PDB | Homo sapiens (Human) | Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A |
| 2 | A, B, C, D | N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide | non-polymer | 393.5 | 4 | Chemie (A17) |
Sequence modifications
A, B, C, D: 1 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Glu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 167995.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1573.9 | |
| All* | Total formula weight | 169569.7 |
