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3DRQ

Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 FP-MPER Hyb3K construct 514GIGALFLGFLGAAGS528KK-Ahx-655KNEQELLELDKWASLWN671 soaked in PEG/2-propanol solution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
2F5 Fab' light chainpolymer21423363.81Homo sapiens (human)
2B
(B)
2F5 Fab' heavy chainpolymer23524985.41Pfam (PF07654)
UniProt (by SIFTS) (Q6PYX1)
Homo sapiens (human)
3C
(C)
gp41 peptide epitopepolymer353822.41
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E, F, G
(A, B, C)
waterwater18.0234Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight52171.7
Non-Polymers*Number of molecules1
Total formula weight92.1
All*Total formula weight52263.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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