3DPY
Protein farnesyltransferase complexed with FPP and caged TKCVIM substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | polymer | 377 | 44098.1 | 1 | UniProt (Q04631) Pfam (PF01239) | Rattus norvegicus (brown rat rat rats) | CAAX farnesyltransferase subunit alpha, Ras proteins prenyltransferase alpha, FTase-alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha |
| 2 | B (B) | Protein farnesyltransferase subunit beta | polymer | 437 | 48722.3 | 1 | UniProt (Q02293) Pfam (PF00432) | Rattus norvegicus (brown rat rat rats) | FTase-beta, CAAX farnesyltransferase subunit beta, RAS proteins prenyltransferase beta |
| 3 | C (C) | caged substrate | polymer | 6 | 694.9 | 1 | |||
| 4 | D (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (B) | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 1 | Chemie (FPP) | |||
| 6 | F (B) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 7 | G, H, I (A, B, C) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93515.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 507.8 | |
| All* | Total formula weight | 94023.1 |
