3DP6

Crystal structure of the binding domain of the AMPA subunit GluR2 bound to glutamate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Glutamate receptor 2	polymer	279	30810.4	3	UniProt (P19491) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus	GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2
2	D, E, G, H, J... (A, B, C)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	F, I, L (A, B, C)	GLUTAMIC ACID	non-polymer		147.1	3	Chemie (GLU)
4	M, N, O (A, B, C)	water	water		18.0	673	Chemie (HOH)

Sequence modifications

A, B, C: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Leu -15	-	expression tag
Val -14	-	expression tag
Pro -13	-	expression tag
Arg -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Ala -9	-	expression tag
Met -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Gly -5	-	expression tag
Asn -4	-	expression tag
Asp -3	-	expression tag
Thr -2	-	expression tag
Ser -1	-	expression tag
Arg 0	-	expression tag
Gly 1	-	expression tag
Ala 2	-	expression tag

A, B, C: 120 - 263 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Gly 262	-	expression tag
Ser 263	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	92431.3
Non-Polymers*	Number of molecules	9
	Total formula weight	833.8
All*	Total formula weight	93265.2

*Water molecules are not included.