3DN5
Aldose Reductase in complex with novel biarylic inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aldose reductase | polymer | 316 | 35898.3 | 1 | UniProt (P15121) Pfam (PF00248) | Homo sapiens (Human) | AR, Aldehyde reductase |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C (A) | 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid | non-polymer | 277.3 | 1 | Chemie (53N) | |||
| 4 | D (A) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35898.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1020.7 | |
| All* | Total formula weight | 36919.0 |
