3DKO
Complex between the kinase domain of human ephrin type-a receptor 7 (epha7) and inhibitor alw-ii-49-7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin type-A receptor 7 | polymer | 318 | 36239.5 | 1 | UniProt (Q15375) Pfam (PF14575) Pfam (PF07714) | Homo sapiens (Human) | Tyrosine-protein kinase receptor EHK-3, EPH homology kinase 3, Receptor protein-tyrosine kinase HEK11 |
| 2 | B (A) | 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide | non-polymer | 414.4 | 1 | Chemie (IHZ) | |||
| 3 | C (A) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 590 - 899 (UniProt: Q15375)
| PDB | External Database | Details |
|---|---|---|
| Met 589 | - | expression tag |
| Ala 900 | - | expression tag |
| His 901 | - | expression tag |
| His 902 | - | expression tag |
| His 903 | - | expression tag |
| His 904 | - | expression tag |
| His 905 | - | expression tag |
| His 906 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36239.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 414.4 | |
| All* | Total formula weight | 36653.9 |
