3DHD
Crystal structure of human NAMPT complexed with nicotinamide mononucleotide and pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nicotinamide phosphoribosyltransferase | polymer | 484 | 54805.1 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) | Homo sapiens | NAmPRTase, Nampt, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1, Visfatin |
| 2 | C, D, G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 3 | E, J (A, B) | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | non-polymer | 335.2 | 2 | Chemie (NMN) PubChem (939) PubChem (9819044) PubChem (44269211) PubChem (177675032) PubChem (46874984) PubChem (14181) PubChem (90476335) PubChem (6093202) PubChem (15737496) PubChem (71750998) PubChem (89516131) PubChem (93605785) PubChem (122587981) PubChem (123929622) PubChem (124350426) PubChem (134694109) PubChem (147327152) PubChem (149999359) PubChem (164745794) PubChem (167012155) PubChem (172887170) | |||
| 4 | F, I (A, B) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 2 | Chemie (POP) PubChem (4995) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109610.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1119.6 | |
| All* | Total formula weight | 110729.8 |
