3DHD
Crystal structure of human NAMPT complexed with nicotinamide mononucleotide and pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nicotinamide phosphoribosyltransferase | polymer | 484 | 54805.1 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) | Homo sapiens | NAmPRTase, Nampt, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1, Visfatin |
| 2 | C, D, G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | E, J (A, B) | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | non-polymer | 335.2 | 2 | Chemie (NMN) | |||
| 4 | F, I (A, B) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 2 | Chemie (POP) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109610.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1119.6 | |
| All* | Total formula weight | 110729.8 |
