3DD8
Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD-486019 with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) | Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C, CAC | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MERCURY (II) ION | non-polymer | 200.6 | 1 | Chemie (HG) | |||
| 4 | D (A) | 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate | non-polymer | 371.5 | 1 | Chemie (2C7) | |||
| 5 | E (A) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29289.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 637.5 | |
| All* | Total formula weight | 29926.5 |
