3DAU
Crystal structure of the ternary MTX NADPH complex of Escherichia coli dihydrofolate reductase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydrofolate reductase | polymer | 159 | 18019.3 | 1 | UniProt (P0ABQ4) Pfam (PF00186) In PDB | Escherichia coli | |
| 2 | A | METHOTREXATE | non-polymer | 454.4 | 1 | Chemie (MTX) | |||
| 3 | A | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18019.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1199.9 | |
| All* | Total formula weight | 19219.2 |
