3D97
Crystal Structure of the R132K:R111L:L121E Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II At 1.50 Angstroms Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15525.7 | 2 | UniProt (P29373) Pfam (PF00061) | Homo sapiens (human) | Cellular retinoic acid-binding protein II, CRABP-II, Retinoic acid-binding protein II, cellular |
| 2 | C (A) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 3 | D, E (B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Leu 111 | Arg 112 | engineered mutation |
| Glu 121 | Leu 122 | engineered mutation |
| Lys 132 | Arg 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31051.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 328.3 | |
| All* | Total formula weight | 31379.7 |
