3D6T
Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Leucine-rich repeat serine/threonine-protein kinase 2 | polymer | 171 | 19803.0 | 1 | UniProt (Q5S007) Pfam (PF08477) | Homo sapiens (Human) | Dardarin |
| 2 | B (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D (B) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
B: 1336 - 1505 (UniProt: Q5S007)
| PDB | External Database | Details |
|---|---|---|
| Mse 1335 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19803.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 467.5 | |
| All* | Total formula weight | 20270.5 |
