3D3X

Crystal structure of botulinum neurotoxin serotype E catalytic domain in complex with SNAP-25 substrate peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Type E botulinum toxin	polymer	427	48673.8	2	UniProt (Q9K395) Pfam (PF01742)	Clostridium butyricum
2	C, D (C, D)	SNAP-25 substrate peptide	polymer	5	546.7	2
3	E, L (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	F, G, H, I, J... (A, B)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
5	O, P, Q (A, B, D)	water	water		18.0	251	Chemie (HOH)

Sequence modifications

A, B: 1 - 421 (UniProt: Q9K395)

PDB	External Database	Details
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	98441.1
Non-Polymers*	Number of molecules	10
	Total formula weight	899.3
All*	Total formula weight	99340.4

*Water molecules are not included.