3D2W
Crystal structure of mouse TDP-43 RRM2 domain in complex with DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | TAR DNA-binding protein 43 | polymer | 89 | 10097.5 | 1 | UniProt (Q921F2) Pfam (PF00076) In PDB | Mus musculus (mouse) | TDP-43, RRM2 domain of mouse TDP-43 |
2 | B | DNA (5'-D(*DGP*DTP*DTP*DGP*DAP*DGP*DCP*DGP*DTP*DT)-3') | polymer | 10 | 3091.0 | 1 | |||
3 | B | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 192 - 265 (UniProt: Q921F2)
PDB | External Database | Details |
---|---|---|
Met 180 | - | expression tag |
Arg 181 | - | expression tag |
Gly 182 | - | expression tag |
Ser 183 | - | expression tag |
His 184 | - | expression tag |
His 185 | - | expression tag |
His 186 | - | expression tag |
His 187 | - | expression tag |
His 188 | - | expression tag |
His 189 | - | expression tag |
Gly 190 | - | expression tag |
Ser 191 | - | expression tag |
Lys 266 | - | expression tag |
Leu 267 | - | expression tag |
Asn 268 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13188.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 95.0 | |
All* | Total formula weight | 13283.5 |