3D29
Proteasome Inhibition by Fellutamide B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O | PRE8 isoform 1 | polymer | 250 | 27191.8 | 2 | UniProt (A0A6L1BIF8) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23639) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 2 | B, P | PRE9 isoform 1 | polymer | 244 | 27050.4 | 2 | UniProt (A0A6A5PXC6) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23638) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 3 | C, Q | PRE6 isoform 1 | polymer | 241 | 26903.3 | 2 | UniProt (A0A6A5Q273) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P40303) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 4 | D, R | PUP2 isoform 1 | polymer | 242 | 26544.8 | 2 | UniProt (A0A6A5PXN2) Pfam (PF00227) Pfam (PF10584) UniProt (by SIFTS) (P32379) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 5 | E, S | PRE5 isoform 1 | polymer | 233 | 25502.8 | 2 | UniProt (A0A6A5PTH4) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P40302) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 6 | F, T | PRE10 isoform 1 | polymer | 244 | 26892.5 | 2 | UniProt (A0A6A5Q4M4) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21242) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 7 | G, U | SCL1 isoform 1 | polymer | 243 | 27316.0 | 2 | UniProt (A0A6A5PYC9) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21243) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 8 | H, V | proteasome endopeptidase complex | polymer | 222 | 23987.3 | 2 | UniProt (A0A6A5Q449) Pfam (PF00227) Pfam (PF12465) UniProt (by SIFTS) (P25043) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 9 | I, W | PUP3 isoform 1 | polymer | 204 | 22496.6 | 2 | UniProt (A0A6L0YA22) Pfam (PF00227) UniProt (by SIFTS) (P25451) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 10 | J, X | Proteasome subunit beta | polymer | 198 | 22545.7 | 2 | UniProt (A0A6A5Q0W2) Pfam (PF00227) UniProt (by SIFTS) (P22141) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 11 | K, Y | proteasome endopeptidase complex | polymer | 212 | 23325.2 | 2 | UniProt (A0A6A5Q5W3) Pfam (PF00227) UniProt (by SIFTS) (P30656) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 12 | L, Z | PRE7 isoform 1 | polymer | 222 | 24883.9 | 2 | UniProt (A0A6A5Q0P3) Pfam (PF00227) UniProt (by SIFTS) (P23724) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 13 | M, 1 | Proteasome subunit beta | polymer | 233 | 25945.5 | 2 | UniProt (A0A8H8ULD3) Pfam (PF00227) UniProt (by SIFTS) (P30657) In PDB | Saccharomyces cerevisiae (brewer's yeast) | |
| 14 | N, 2 | Proteasome subunit beta type-1 | polymer | 196 | 21517.2 | 2 | UniProt (P38624) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
| 15 | a, b, c, d, e... | Fellutamide B | polymer | 3 | 373.4 | 6 | synthetic construct | ||
| 16 | a, b, c, d, e... | (3R)-3-HYDROXYDODECANOIC ACID | non-polymer | 216.3 | 6 | Chemie (HXD) | |||
| 17 | water | water | 18.0 | 1332 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 34 |
| Total formula weight | 706446.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1297.9 | |
| All* | Total formula weight | 707744.6 |
