3D29
Proteasome Inhibition by Fellutamide B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O (A, O) | PRE8 isoform 1 | polymer | 250 | 27191.8 | 2 | UniProt (A0A6L1BIF8) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23639) | Saccharomyces cerevisiae (brewer's yeast) | |
| 2 | B, P (B, P) | PRE9 isoform 1 | polymer | 244 | 27050.4 | 2 | UniProt (A0A6A5PXC6) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23638) | Saccharomyces cerevisiae (brewer's yeast) | |
| 3 | C, Q (C, Q) | PRE6 isoform 1 | polymer | 241 | 26903.3 | 2 | UniProt (A0A6A5Q273) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P40303) | Saccharomyces cerevisiae (brewer's yeast) | |
| 4 | D, R (D, R) | PUP2 isoform 1 | polymer | 242 | 26544.8 | 2 | UniProt (A0A6A5PXN2) Pfam (PF00227) Pfam (PF10584) UniProt (by SIFTS) (P32379) | Saccharomyces cerevisiae (brewer's yeast) | |
| 5 | E, S (E, S) | PRE5 isoform 1 | polymer | 233 | 25502.8 | 2 | UniProt (A0A6A5PTH4) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P40302) | Saccharomyces cerevisiae (brewer's yeast) | |
| 6 | F, T (F, T) | PRE10 isoform 1 | polymer | 244 | 26892.5 | 2 | UniProt (A0A6A5Q4M4) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21242) | Saccharomyces cerevisiae (brewer's yeast) | |
| 7 | G, U (G, U) | SCL1 isoform 1 | polymer | 243 | 27316.0 | 2 | UniProt (A0A6A5PYC9) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21243) | Saccharomyces cerevisiae (brewer's yeast) | |
| 8 | H, V (H, V) | proteasome endopeptidase complex | polymer | 222 | 23987.3 | 2 | UniProt (A0A6A5Q449) Pfam (PF00227) Pfam (PF12465) UniProt (by SIFTS) (P25043) | Saccharomyces cerevisiae (brewer's yeast) | |
| 9 | I, W (I, W) | PUP3 isoform 1 | polymer | 204 | 22496.6 | 2 | UniProt (A0A6L0YA22) Pfam (PF00227) UniProt (by SIFTS) (P25451) | Saccharomyces cerevisiae (brewer's yeast) | |
| 10 | J, X (J, X) | Proteasome subunit beta | polymer | 198 | 22545.7 | 2 | UniProt (A0A6A5Q0W2) Pfam (PF00227) UniProt (by SIFTS) (P22141) | Saccharomyces cerevisiae (brewer's yeast) | |
| 11 | K, Y (K, Y) | proteasome endopeptidase complex | polymer | 212 | 23325.2 | 2 | UniProt (A0A6A5Q5W3) Pfam (PF00227) UniProt (by SIFTS) (P30656) | Saccharomyces cerevisiae (brewer's yeast) | |
| 12 | L, Z (L, Z) | PRE7 isoform 1 | polymer | 222 | 24883.9 | 2 | UniProt (A0A6A5Q0P3) Pfam (PF00227) UniProt (by SIFTS) (P23724) | Saccharomyces cerevisiae (brewer's yeast) | |
| 13 | AA, M (M, 1) | Proteasome subunit beta | polymer | 233 | 25945.5 | 2 | UniProt (A0A8H8ULD3) Pfam (PF00227) UniProt (by SIFTS) (P30657) | Saccharomyces cerevisiae (brewer's yeast) | |
| 14 | BA, N (N, 2) | Proteasome subunit beta type-1 | polymer | 196 | 21517.2 | 2 | UniProt (P38624) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
| 15 | CA, DA, EA, FA, GA... (a, b, c, d, e...) | Fellutamide B | polymer | 3 | 373.4 | 6 | synthetic construct | ||
| 16 | IA, JA, KA, LA, MA... (a, b, c, d, e...) | (3R)-3-HYDROXYDODECANOIC ACID | non-polymer | 216.3 | 6 | Chemie (HXD) | |||
| 17 | AB, BB, CB, DB, EB... (M, N, O, P, Q...) | water | water | 18.0 | 1332 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 34 |
| Total formula weight | 706446.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1297.9 | |
| All* | Total formula weight | 707744.6 |
