3CX5
Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, L (A, L) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 431 | 47445.2 | 2 | UniProt (P07256) Pfam (PF00675) Pfam (PF05193) | Saccharomyces cerevisiae (yeast) | Ubiquinol- cytochrome-c reductase complex core protein 1, Core protein I, Complex III subunit 1 |
| 2 | B, M (B, M) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 352 | 38751.9 | 2 | UniProt (P07257) Pfam (PF00675) | Saccharomyces cerevisiae (yeast) | Ubiquinol- cytochrome-c reductase complex core protein 2, Core protein II, Complex III subunit 2 |
| 3 | C, N (C, N) | CYTOCHROME B | polymer | 385 | 43686.6 | 2 | UniProt (P00163) Pfam (PF00033) Pfam (PF00032) | Saccharomyces cerevisiae (yeast) | |
| 4 | D, O (D, O) | Cytochrome c1, heme protein, mitochondrial | polymer | 248 | 27807.4 | 2 | UniProt (P07143) Pfam (PF02167) | Saccharomyces cerevisiae (yeast) | Cytochrome c-1, Cytochrome b-c1 complex subunit 4, Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit, Complex III subunit 4, Complex III subunit IV |
| 5 | E, P (E, P) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 185 | 20123.0 | 2 | UniProt (P08067) Pfam (PF02921) Pfam (PF00355) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP, Complex III subunit 5 |
| 6 | F, Q (F, Q) | Cytochrome b-c1 complex subunit 6 | polymer | 146 | 17144.9 | 2 | UniProt (P00127) Pfam (PF02320) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase complex 17 kDa protein, Cytochrome c1 non-heme 17 kDa protein, Mitochondrial hinge protein, Complex III subunit 6, Complex III subunit VI |
| 7 | G, R (G, R) | Cytochrome b-c1 complex subunit 7 | polymer | 126 | 14452.6 | 2 | UniProt (P00128) Pfam (PF02271) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase c reductase complex 14 kDa protein, Complex III subunit 7, Complex III subunit VII |
| 8 | H, S (H, S) | Cytochrome b-c1 complex subunit 8 | polymer | 93 | 10856.3 | 2 | UniProt (P08525) Pfam (PF02939) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C, Ubiquinol-cytochrome c reductase complex 11 kDa protein, Complex III subunit VII, Complex III subunit 8 |
| 9 | I, T (I, T) | Cytochrome b-c1 complex subunit 9 | polymer | 65 | 7354.1 | 2 | UniProt (P22289) Pfam (PF05365) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase complex 7.3 kDa protein, Cytochrome c1 non-heme 7.3 kDa protein, Complex III subunit X, Complex III subunit 9 |
| 10 | J, U (J, U) | HEAVY CHAIN (VH) OF FV-FRAGMENT | polymer | 127 | 14365.8 | 2 | Mus musculus (house mouse) | ||
| 11 | K, V (K, V) | LIGHT CHAIN (VL) OF FV-FRAGMENT | polymer | 107 | 11926.4 | 2 | Mus musculus (house mouse) | ||
| 12 | W (W) | Cytochrome c iso-1 | polymer | 108 | 12115.9 | 1 | UniProt (P00044) Pfam (PF00034) | Saccharomyces cerevisiae (yeast) | |
| 13 | X (X) | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900003) | sucrose | ||
| 14 | KA, Y (L, A) | (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate | non-polymer | 592.8 | 2 | Chemie (6PH) PubChem (78184123) PubChem (447791) | |||
| 15 | LA, Z (L, A) | UNDECYL-MALTOSIDE | non-polymer | 496.6 | 2 | Chemie (UMQ) PubChem (44462510) PubChem (46936455) PubChem (70699426) PubChem (70699431) PubChem (70796434) PubChem (71300307) PubChem (58112566) PubChem (59518662) PubChem (124643296) PubChem (68343856) PubChem (70699429) PubChem (70701336) PubChem (70701337) PubChem (70839940) PubChem (70841479) PubChem (70863062) PubChem (71300308) PubChem (89952000) PubChem (92132109) PubChem (447793) PubChem (5076192) PubChem (126731015) PubChem (126731038) PubChem (126735855) PubChem (126735857) PubChem (131632466) PubChem (169544249) | |||
| 16 | AA, BA, GA, MA, NA... (C, D, N, O, W) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 7 | Chemie (HEM) | |||
| 17 | CA, OA (C, N) | STIGMATELLIN A | non-polymer | 514.6 | 2 | Chemie (SMA) PubChem (49867661) PubChem (45487276) PubChem (5293) PubChem (5326513) PubChem (124383969) PubChem (443658) PubChem (92966532) PubChem (447884) PubChem (101724523) PubChem (124708091) PubChem (5353970) PubChem (124936630) PubChem (124936631) PubChem (125116916) PubChem (6435507) PubChem (159935206) PubChem (162931293) PubChem (162931294) PubChem (162931295) | |||
| 18 | DA, PA (C, N) | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate | non-polymer | 692.0 | 2 | Chemie (8PE) PubChem (447790) PubChem (9546733) | |||
| 19 | EA, QA (C, N) | (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate | non-polymer | 593.8 | 2 | Chemie (9PE) PubChem (24779687) PubChem (138256935) | |||
| 20 | FA (C) | (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate | non-polymer | 634.6 | 1 | Chemie (CN5) PubChem (24779688) | |||
| 21 | HA, TA (D, O) | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate | non-polymer | 564.7 | 2 | Chemie (7PH) PubChem (24779689) PubChem (138276598) | |||
| 22 | IA, RA (D, N) | (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate | non-polymer | 834.9 | 2 | Chemie (CN3) PubChem (24779690) | |||
| 23 | JA, UA (E, P) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 24 | AB, BB, CB, DB, EB... (E, F, G, H, I...) | water | water | 18.0 | 1648 | Chemie (HOH) |
Sequence modifications
A, L: 27 - 457 (UniProt: P07256)
| PDB | External Database | Details |
|---|---|---|
| Asp 153 | Glu 153 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 23 |
| Total formula weight | 519944.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 13880.4 | |
| All* | Total formula weight | 534166.9 |
