3CX5
Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, L (A, L) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 431 | 47445.2 | 2 | UniProt (P07256) Pfam (PF00675) Pfam (PF05193) | Saccharomyces cerevisiae (yeast) | Ubiquinol- cytochrome-c reductase complex core protein 1, Core protein I, Complex III subunit 1 |
| 2 | B, M (B, M) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 352 | 38751.9 | 2 | UniProt (P07257) Pfam (PF00675) | Saccharomyces cerevisiae (yeast) | Ubiquinol- cytochrome-c reductase complex core protein 2, Core protein II, Complex III subunit 2 |
| 3 | C, N (C, N) | CYTOCHROME B | polymer | 385 | 43686.6 | 2 | UniProt (P00163) Pfam (PF00033) Pfam (PF00032) | Saccharomyces cerevisiae (yeast) | |
| 4 | D, O (D, O) | Cytochrome c1, heme protein, mitochondrial | polymer | 248 | 27807.4 | 2 | UniProt (P07143) Pfam (PF02167) | Saccharomyces cerevisiae (yeast) | Cytochrome c-1, Cytochrome b-c1 complex subunit 4, Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit, Complex III subunit 4, Complex III subunit IV |
| 5 | E, P (E, P) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 185 | 20123.0 | 2 | UniProt (P08067) Pfam (PF02921) Pfam (PF00355) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP, Complex III subunit 5 |
| 6 | F, Q (F, Q) | Cytochrome b-c1 complex subunit 6 | polymer | 146 | 17144.9 | 2 | UniProt (P00127) Pfam (PF02320) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase complex 17 kDa protein, Cytochrome c1 non-heme 17 kDa protein, Mitochondrial hinge protein, Complex III subunit 6, Complex III subunit VI |
| 7 | G, R (G, R) | Cytochrome b-c1 complex subunit 7 | polymer | 126 | 14452.6 | 2 | UniProt (P00128) Pfam (PF02271) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase c reductase complex 14 kDa protein, Complex III subunit 7, Complex III subunit VII |
| 8 | H, S (H, S) | Cytochrome b-c1 complex subunit 8 | polymer | 93 | 10856.3 | 2 | UniProt (P08525) Pfam (PF02939) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C, Ubiquinol-cytochrome c reductase complex 11 kDa protein, Complex III subunit VII, Complex III subunit 8 |
| 9 | I, T (I, T) | Cytochrome b-c1 complex subunit 9 | polymer | 65 | 7354.1 | 2 | UniProt (P22289) Pfam (PF05365) | Saccharomyces cerevisiae (yeast) | Ubiquinol-cytochrome c reductase complex 7.3 kDa protein, Cytochrome c1 non-heme 7.3 kDa protein, Complex III subunit X, Complex III subunit 9 |
| 10 | J, U (J, U) | HEAVY CHAIN (VH) OF FV-FRAGMENT | polymer | 127 | 14365.8 | 2 | Mus musculus (house mouse) | ||
| 11 | K, V (K, V) | LIGHT CHAIN (VL) OF FV-FRAGMENT | polymer | 107 | 11926.4 | 2 | Mus musculus (house mouse) | ||
| 12 | W (W) | Cytochrome c iso-1 | polymer | 108 | 12115.9 | 1 | UniProt (P00044) Pfam (PF00034) | Saccharomyces cerevisiae (yeast) | |
| 13 | X (X) | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900003) | sucrose | ||
| 14 | KA, Y (L, A) | (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate | non-polymer | 592.8 | 2 | Chemie (6PH) | |||
| 15 | LA, Z (L, A) | UNDECYL-MALTOSIDE | non-polymer | 496.6 | 2 | Chemie (UMQ) | |||
| 16 | AA, BA, GA, MA, NA... (C, D, N, O, W) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 7 | Chemie (HEM) | |||
| 17 | CA, OA (C, N) | STIGMATELLIN A | non-polymer | 514.6 | 2 | Chemie (SMA) | |||
| 18 | DA, PA (C, N) | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate | non-polymer | 692.0 | 2 | Chemie (8PE) | |||
| 19 | EA, QA (C, N) | (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate | non-polymer | 593.8 | 2 | Chemie (9PE) | |||
| 20 | FA (C) | (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate | non-polymer | 634.6 | 1 | Chemie (CN5) | |||
| 21 | HA, TA (D, O) | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate | non-polymer | 564.7 | 2 | Chemie (7PH) | |||
| 22 | IA, RA (D, N) | (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate | non-polymer | 834.9 | 2 | Chemie (CN3) | |||
| 23 | JA, UA (E, P) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 24 | AB, BB, CB, DB, EB... (E, F, G, H, I...) | water | water | 18.0 | 1648 | Chemie (HOH) |
Sequence modifications
A, L: 27 - 457 (UniProt: P07256)
| PDB | External Database | Details |
|---|---|---|
| Asp 153 | Glu 153 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 23 |
| Total formula weight | 519944.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 13880.4 | |
| All* | Total formula weight | 534166.9 |
