3CU0

human beta 1,3-glucuronyltransferase I (GlcAT-I) in complex with UDP and GAL-GAL(6-SO4)-XYL(2-PO4)-O-SER

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3	polymer	281	31163.4	2	UniProt (O94766) Pfam (PF03360)	Homo sapiens (human)	Beta-1,3-glucuronyltransferase 3, Glucuronosyltransferase-I, GlcAT-I, UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase, GlcUAT-I
2	C, D (C, D)	beta-D-galactopyranose-(1-3)-beta-D-galactopyranose	branched		342.3	2	In PDB GlyTouCan (G95894VW)
3	E, J (A, B)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
4	F, I (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	G, H (A)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	2	Chemie (UDP)
6	K, L (A, B)	water	water		18.0	281	Chemie (HOH)

Sequence modifications

A, B: 76 - 335 (UniProt: O94766)

PDB	External Database	Details
Met 55	-	expression tag
Gly 56	-	expression tag
Ser 57	-	expression tag
Ser 58	-	expression tag
His 59	-	expression tag
His 60	-	expression tag
His 61	-	expression tag
His 62	-	expression tag
His 63	-	expression tag
His 64	-	expression tag
Ser 65	-	expression tag
Ser 66	-	expression tag
Gly 67	-	expression tag
Leu 68	-	expression tag
Val 69	-	expression tag
Pro 70	-	expression tag
Arg 71	-	expression tag
Gly 72	-	expression tag
Ser 73	-	expression tag
His 74	-	expression tag
Met 75	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62326.9
Branched	Number of molecules	2
	Total formula weight	684.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1110.3
All*	Total formula weight	64121.8

*Water molecules are not included.