3CU0

human beta 1,3-glucuronyltransferase I (GlcAT-I) in complex with UDP and GAL-GAL(6-SO4)-XYL(2-PO4)-O-SER

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015018	molecular_function	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
A	0016020	cellular_component	membrane
B	0015018	molecular_function	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
B	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Region: {"description":"Interaction with galactose moiety of substrate glycoprotein"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	46
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	20
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"11950836","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	20
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	4
Details	Site: {"description":"Interaction with galactose moiety of substrate glycoprotein"}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine"}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1kws

Chain	Residue	Details
A	GLU281

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1kws

Chain	Residue	Details
B	GLU281

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site_id	MCSA1
Number of Residues	2
Details	M-CSA 801

Chain	Residue	Details
A	ASP196	metal ligand
A	GLU281	proton acceptor, proton donor

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site_id	MCSA2
Number of Residues	2
Details	M-CSA 801

Chain	Residue	Details
B	ASP196	metal ligand
B	GLU281	proton acceptor, proton donor

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