3CL2
N1 Neuraminidase N294S + Oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Neuraminidase | polymer | 385 | 42157.9 | 8 | UniProt (Q6DPL2) | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) | |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 8 | Chemie (G39) PubChem (40640967) PubChem (40640969) PubChem (40640971) PubChem (44345914) PubChem (40640973) PubChem (449381) PubChem (58753598) PubChem (4631786) PubChem (71038155) PubChem (71065667) PubChem (95162772) PubChem (121452907) PubChem (124637832) PubChem (129886749) PubChem (134694948) PubChem (137378365) |
Sequence modifications
A, B, C, D, E, F, G, H: 83 - 468 (UniProt: Q6DPL2)
| PDB | External Database | Details |
|---|---|---|
| Tyr 252 | His 233 | conflict |
| Ser 294 | Asn 275 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 337263.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2274.8 | |
| All* | Total formula weight | 339537.9 |
