3CJO
Crystal structure of KSP in complex with inhibitor 30
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kinesin-like protein KIF11 | polymer | 367 | 40924.4 | 2 | UniProt (P52732) Pfam (PF00225) | Homo sapiens (Human) | Kinesin-related motor protein Eg5, Kinesin-like spindle protein HKSP, Thyroid receptor-interacting protein 5, TRIP-5, Kinesin-like protein 1 |
| 2 | C, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, G (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | E, H (A, B) | (2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide | non-polymer | 459.5 | 2 | Chemie (K30) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81848.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1822.0 | |
| All* | Total formula weight | 83670.8 |
