3CHN

Solution structure of human secretory IgA1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (L, M, N, O)	Immunoglobulin kappa light chain	polymer	214	23216.8	4		Homo sapiens (human)
2	E, F, G, H (A, B, D, C)	Ig alpha-1 chain C region	polymer	475	51068.4	4	UniProt (P01876) Pfam (PF07654) Pfam (PF00047)	Homo sapiens (human)
3	I (J)	Secretory component	polymer	106	11850.5	1	UniProt (P01833) Pfam (PF07686)	Homo sapiens (human)	Poly-Ig receptor, PIGR, Hepatocellular carcinoma-associated protein TB6
4	J (S)	Secretory component	polymer	585	64355.2	1	UniProt (P01833) Pfam (PF07686)	Homo sapiens (human)	Poly-Ig receptor, PIGR, Hepatocellular carcinoma-associated protein TB6

Sequence modifications

A, B, D, C: 123 - 475 (UniProt: P01876)

PDB	External Database	Details
Gln 1	-	SEE REMARK 999
Val 2	-	SEE REMARK 999
Lys 3	-	SEE REMARK 999
Leu 4	-	SEE REMARK 999
Leu 5	-	SEE REMARK 999
Glu 6	-	SEE REMARK 999
Gln 7	-	SEE REMARK 999
Ser 8	-	SEE REMARK 999
Gly 9	-	SEE REMARK 999
Ala 10	-	SEE REMARK 999
Glu 11	-	SEE REMARK 999
Val 12	-	SEE REMARK 999
Lys 13	-	SEE REMARK 999
Lys 14	-	SEE REMARK 999
Pro 15	-	SEE REMARK 999
Gly 16	-	SEE REMARK 999
Ala 17	-	SEE REMARK 999
Ser 18	-	SEE REMARK 999
Val 19	-	SEE REMARK 999
Lys 20	-	SEE REMARK 999
Val 21	-	SEE REMARK 999
Ser 22	-	SEE REMARK 999
Cys 23	-	SEE REMARK 999
Lys 24	-	SEE REMARK 999
Ala 25	-	SEE REMARK 999
Ser 26	-	SEE REMARK 999
Gly 27	-	SEE REMARK 999
Tyr 28	-	SEE REMARK 999
Ser 29	-	SEE REMARK 999
Phe 30	-	SEE REMARK 999
Thr 31	-	SEE REMARK 999
Ser 32	-	SEE REMARK 999
Tyr 33	-	SEE REMARK 999
Gly 34	-	SEE REMARK 999
Leu 35	-	SEE REMARK 999
His 36	-	SEE REMARK 999
Trp 37	-	SEE REMARK 999
Val 38	-	SEE REMARK 999
Arg 39	-	SEE REMARK 999
Gln 40	-	SEE REMARK 999
Ala 41	-	SEE REMARK 999
Pro 42	-	SEE REMARK 999
Gly 43	-	SEE REMARK 999
Gln 44	-	SEE REMARK 999
Arg 45	-	SEE REMARK 999
Leu 46	-	SEE REMARK 999
Glu 47	-	SEE REMARK 999
Trp 48	-	SEE REMARK 999
Met 49	-	SEE REMARK 999
Gly 50	-	SEE REMARK 999
Trp 51	-	SEE REMARK 999
Ile 52	-	SEE REMARK 999
Ser 53	-	SEE REMARK 999
Ala 54	-	SEE REMARK 999
Gly 55	-	SEE REMARK 999
Thr 56	-	SEE REMARK 999
Gly 57	-	SEE REMARK 999
Asn 58	-	SEE REMARK 999
Thr 59	-	SEE REMARK 999
Lys 60	-	SEE REMARK 999
Tyr 61	-	SEE REMARK 999
Ser 62	-	SEE REMARK 999
Gln 63	-	SEE REMARK 999
Lys 64	-	SEE REMARK 999
Phe 65	-	SEE REMARK 999
Arg 66	-	SEE REMARK 999
Gly 67	-	SEE REMARK 999
Arg 68	-	SEE REMARK 999
Val 69	-	SEE REMARK 999
Thr 70	-	SEE REMARK 999
Phe 71	-	SEE REMARK 999
Thr 72	-	SEE REMARK 999
Arg 73	-	SEE REMARK 999
Asp 74	-	SEE REMARK 999
Thr 75	-	SEE REMARK 999
Ser 76	-	SEE REMARK 999
Ala 77	-	SEE REMARK 999
Thr 78	-	SEE REMARK 999
Thr 79	-	SEE REMARK 999
Ala 80	-	SEE REMARK 999
Tyr 81	-	SEE REMARK 999
Met 82	-	SEE REMARK 999
Gly 83	-	SEE REMARK 999
Leu 84	-	SEE REMARK 999
Ser 85	-	SEE REMARK 999
Ser 86	-	SEE REMARK 999
Leu 87	-	SEE REMARK 999
Arg 88	-	SEE REMARK 999
Pro 89	-	SEE REMARK 999
Glu 90	-	SEE REMARK 999
Asp 91	-	SEE REMARK 999
Thr 92	-	SEE REMARK 999
Ala 93	-	SEE REMARK 999
Val 94	-	SEE REMARK 999
Tyr 95	-	SEE REMARK 999
Tyr 96	-	SEE REMARK 999
Cys 97	-	SEE REMARK 999
Ala 98	-	SEE REMARK 999
Arg 99	-	SEE REMARK 999
Asp 100	-	SEE REMARK 999
Pro 101	-	SEE REMARK 999
Tyr 102	-	SEE REMARK 999
Gly 103	-	SEE REMARK 999
Gly 104	-	SEE REMARK 999
Gly 105	-	SEE REMARK 999
Lys 106	-	SEE REMARK 999
Ser 107	-	SEE REMARK 999
Glu 108	-	SEE REMARK 999
Phe 109	-	SEE REMARK 999
Asp 110	-	SEE REMARK 999
Tyr 111	-	SEE REMARK 999
Trp 112	-	SEE REMARK 999
Gly 113	-	SEE REMARK 999
Gln 114	-	SEE REMARK 999
Gly 115	-	SEE REMARK 999
Thr 116	-	SEE REMARK 999
Leu 117	-	SEE REMARK 999
Val 118	-	SEE REMARK 999
Thr 119	-	SEE REMARK 999
Val 120	-	SEE REMARK 999
Ser 121	-	SEE REMARK 999
Ser 122	-	SEE REMARK 999

J: 335 - 440 (UniProt: P01833)

PDB	External Database	Details
Ser 347	Gly 365	variant

S: 1 - 585 (UniProt: P01833)

PDB	External Database	Details
Ser 347	Gly 365	variant

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	373346.4
All*	Total formula weight	373346.4

*Water molecules are not included.