3CFK

Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (L, A, C, E, G...)	CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN,Uncharacterized protein	polymer	216	23258.8	8	UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654)	Mus musculus (mouse)
2	B, D, F, H, J... (H, B, D, F, I...)	CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein	polymer	227	24701.8	8	UniProt (A8K008) Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (Q6N089)	Mus musculus (mouse)
3	AA, BA, CA, DA, FA... (D, E, G, J, K...)	CADMIUM ION	non-polymer		112.4	23	Chemie (CD)
4	EA, V (E, A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	OA, QA (M, O)	2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		282.3	2	Chemie (B3P)
6	AB, BB, CB, DB, EB... (I, J, K, M, N...)	water	water		18.0	277	Chemie (HOH)

Sequence modifications

L, A, C, E, G, J, M, O: 1 - 105 (PDB: 3CFK)
L, A, C, E, G, J, M, O: 106 - 214 (UniProt: Q8TCD0)
H, B, D, F, I, K, N, P: 1 - 103 (PDB: 3CFK)
H, B, D, F, I, K, N, P: 104 - 231 (UniProt: A8K008)

PDB	External Database	Details
Ser 108	Thr 137	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	383685.1
Non-Polymers*	Number of molecules	27
	Total formula weight	3334.3
All*	Total formula weight	387019.4

*Water molecules are not included.