3CFK

Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
C	0005576	cellular_component	extracellular region
C	0005886	cellular_component	plasma membrane
E	0005576	cellular_component	extracellular region
E	0005886	cellular_component	plasma membrane
G	0005576	cellular_component	extracellular region
G	0005886	cellular_component	plasma membrane
J	0005576	cellular_component	extracellular region
J	0005886	cellular_component	plasma membrane
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
M	0005576	cellular_component	extracellular region
M	0005886	cellular_component	plasma membrane
O	0005576	cellular_component	extracellular region
O	0005886	cellular_component	plasma membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD L 301

Chain	Residue
J	GLY57
L	GLN79
L	THR80
L	GLU81
L	HOH341
L	HOH344

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD L 319

Chain	Residue
L	HOH335
J	HOH324
J	HOH332
L	HOH330

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD L 323

Chain	Residue
H	HIS172
L	ASN138
L	HOH333

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 317

Chain	Residue
A	GLN79
A	GLU81
A	HOH411
A	HOH416
M	GLY57

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 318

Chain	Residue
A	ASP69
A	HOH403
J	HOH330

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD B 306

Chain	Residue
B	GLU226
H	GLU226

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD C 308

Chain	Residue
C	GLN79
C	THR80
C	GLU81
C	HOH322
G	GLY57

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD C 309

Chain	Residue
C	ASN138
D	HIS172

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD C 310

Chain	Residue
C	ASN152
C	HOH313
C	HOH316
C	HOH317
C	HOH341
G	ASN152

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD D 311

Chain	Residue
D	ASP65
L	ASP185

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD D 312

Chain	Residue
D	GLU226
P	GLU226

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD E 314

Chain	Residue
E	GLN79
E	GLU81
E	HOH407
O	GLY57

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD E 322

Chain	Residue
E	ASN137
E	ASN138
E	HOH410
F	HIS172

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD G 307

Chain	Residue
C	GLY57
G	GLN79
G	THR80
G	GLU81
G	HOH335
G	HOH338

---

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD G 315

Chain	Residue
G	ASN138
I	HIS172

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD G 320

Chain	Residue
C	GLU81
C	HOH319
C	HOH329
G	HOH327

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD G 321

Chain	Residue
G	SER14
G	GLU17
G	HOH347

---

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD J 302

Chain	Residue
J	ASN138
K	HIS172

---

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD J 303

Chain	Residue
J	ASN152
J	HOH320
J	HOH322
J	HOH347
J	HOH351
L	ASN152

---

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD J 316

Chain	Residue
J	GLN79
J	THR80
J	GLU81
J	HOH340
L	GLY57

---

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD K 304

Chain	Residue
G	ASP185
G	HOH343
K	ASP65

---

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD M 305

Chain	Residue
A	GLY57
M	GLN79
M	GLU81
M	HOH506

---

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD O 313

Chain	Residue
E	GLY57
O	GLN79
O	GLU81
O	HOH505

---

site_id	CC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE B3P M 501

Chain	Residue
E	SER203
E	PRO204
L	ASP69
L	ARG70
M	ASP69
M	ARG70
M	HOH515

---

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE B3P O 502

Chain	Residue
O	ARG70
A	SER203
A	PRO204
G	ASP69
G	ARG70
O	ASP69

---

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 402

Chain	Residue
A	GLU81
M	GLU81

---

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL E 403

Chain	Residue
E	GLU81
E	HOH406
O	GLU81

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR206-HIS212
L	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	744
Details	Domain: {"description":"Ig-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	776
Details	Region: {"description":"CH1","evidences":[{"source":"PubMed","id":"15572068","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	160
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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