3CEH
Human liver glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE5688
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen phosphorylase, liver form | polymer | 809 | 93063.6 | 2 | UniProt (P06737) Pfam (PF00343) | Homo sapiens (human) | |
| 2 | C, G (A, B) | N-acetyl-beta-D-glucopyranosylamine | non-polymer | 221.2 | 2 | Chemie (NBG) PubChem (18656113) PubChem (21308223) PubChem (40549451) PubChem (40549452) PubChem (44335486) PubChem (151446) PubChem (51415028) PubChem (51415029) PubChem (53907776) PubChem (445382) PubChem (3832189) PubChem (10376202) PubChem (101259527) PubChem (9815885) PubChem (124385630) PubChem (13422336) PubChem (124799500) PubChem (124799501) PubChem (129406184) PubChem (135075397) | |||
| 3 | D, H (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) PubChem (1061) | |||
| 4 | E, J (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) PubChem (1051) | |||
| 5 | F, K (A, B) | 4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid | non-polymer | 438.7 | 2 | Chemie (AVE) PubChem (16070039) | |||
| 6 | I (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) PubChem (4478249) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 508 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 186127.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2199.3 | |
| All* | Total formula weight | 188326.4 |
