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3CE0

Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor PJ34

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APoly [ADP-ribose] polymerase 3polymer35739752.11UniProt (Q9Y6F1)
Pfam (PF02877)
Pfam (PF00644)
In PDB
Homo sapiens (human)PARP-3, NAD(+) ADP-ribosyltransferase 3, Poly[ADP-ribose] synthetase 3, pADPRT-3, hPARP-3, IRT1
2AN~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDEnon-polymer295.31Chemie (P34)
Sequence modifications
A: 178 - 532 (UniProt: Q9Y6F1)
PDBExternal DatabaseDetails
Ser 176-expression tag
Met 177-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39752.1
Non-Polymers*Number of molecules1
Total formula weight295.3
All*Total formula weight40047.4
*Water molecules are not included.

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PDB entries from 2024-08-21

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