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3CD3

Crystal structure of phosphorylated human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proto-oncogene tyrosine-protein kinase Fes/Fpspolymer37742838.01UniProt (P07332)
Pfam (PF00017)
Pfam (PF07714)
Homo sapiens (human)C-Fes
2B
(B)
Synthetic peptidepolymer6649.71PDB (3CBL)
3C, D
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4E, F, G
(A)
STAUROSPORINEnon-polymer466.53Chemie (STU)
5H, I
(A, B)
waterwater18.0307Chemie (HOH)
Sequence modifications
A: 448 - 822 (UniProt: P07332)
PDBExternal DatabaseDetails
Ser 446-expression tag
Met 447-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43487.8
Non-Polymers*Number of molecules5
Total formula weight1470.5
All*Total formula weight44958.3
*Water molecules are not included.

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PDB entries from 2025-07-30

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