3CD3
Crystal structure of phosphorylated human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Fes/Fps | polymer | 377 | 42838.0 | 1 | UniProt (P07332) Pfam (PF00017) Pfam (PF07714) | Homo sapiens (human) | C-Fes |
| 2 | B (B) | Synthetic peptide | polymer | 6 | 649.7 | 1 | PDB (3CBL) | ||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 4 | E, F, G (A) | STAUROSPORINE | non-polymer | 466.5 | 3 | Chemie (STU) PubChem (5279) PubChem (71203703) PubChem (42610657) PubChem (44259) PubChem (44299148) PubChem (49831000) PubChem (25322871) PubChem (28684983) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (68262703) PubChem (68306294) PubChem (451705) PubChem (73953205) PubChem (86306248) PubChem (358479) PubChem (5280487) PubChem (5459111) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (6419748) PubChem (9804568) PubChem (122130844) PubChem (12046017) PubChem (9937179) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 307 | Chemie (HOH) |
Sequence modifications
A: 448 - 822 (UniProt: P07332)
| PDB | External Database | Details |
|---|---|---|
| Ser 446 | - | expression tag |
| Met 447 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43487.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1470.5 | |
| All* | Total formula weight | 44958.3 |
