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3CD2

LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADIHYDROFOLATE REDUCTASEpolymer20623918.51UniProt (P16184)
Pfam (PF00186)
In PDB
Pneumocystis cariniiPCDHFR
2ANADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3AMETHOTREXATEnon-polymer454.41Chemie (MTX)
4waterwater18.048Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23918.5
Non-Polymers*Number of molecules2
Total formula weight1197.8
All*Total formula weight25116.4
*Water molecules are not included.

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