3CBJ
Chagasin-Cathepsin B complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin B | polymer | 266 | 29311.6 | 1 | UniProt (P07858) Pfam (PF00112) | Homo sapiens (human) | Cathepsin B1, APP secretase, APPS |
| 2 | B (B) | Chagasin | polymer | 110 | 12054.5 | 1 | UniProt (Q966X9) Pfam (PF09394) | Trypanosoma cruzi | |
| 3 | C, D, E, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A: 57 - 260 (UniProt: P07858)
| PDB | External Database | Details |
|---|---|---|
| Ala 29 | Cys 108 | engineered mutation |
| Ala 110 | His 189 | engineered mutation |
| Ala 115 | Ser 194 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41366.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 379.9 | |
| All* | Total formula weight | 41746.0 |
