3CBC
Crystal structure of Siderocalin (NGAL, Lipocalin 2) Y106F complexed with Ferric Enterobactin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Neutrophil gelatinase-associated lipocalin | polymer | 198 | 22582.0 | 3 | UniProt (P80188) Pfam (PF00061) | Homo sapiens (Human) | NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3 |
| 2 | D, H, K, L, M (A, B, C) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | E, I, N, O, P (A, B, C) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 4 | F, J, Q (A, B, C) | 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID | non-polymer | 241.2 | 3 | Chemie (DBS) | |||
| 5 | G, R, S (A, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | T, U, V (A, B, C) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, B, C: -19 - 178 (UniProt: P80188)
| PDB | External Database | Details |
|---|---|---|
| Ser 87 | Cys 107 | engineered mutation |
| Phe 106 | Tyr 126 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67745.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1595.1 | |
| All* | Total formula weight | 69341.0 |
