3CAV
Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 5beta-pregnan-3,20-dione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-oxo-5-beta-steroid 4-dehydrogenase | polymer | 326 | 37427.9 | 2 | UniProt (P51857) Pfam (PF00248) | Homo sapiens (Human) | Delta(4)-3-ketosteroid 5-beta-reductase, Aldo-keto reductase family 1 member D1 |
| 2 | C, I (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 3 | D, J (A, B) | (5BETA)-PREGNANE-3,20-DIONE | non-polymer | 316.5 | 2 | Chemie (CI2) PubChem (92745) PubChem (92810) PubChem (123867) PubChem (440699) PubChem (7098654) PubChem (7098657) PubChem (11877127) PubChem (11877128) PubChem (11877129) PubChem (11877130) PubChem (13581521) PubChem (13581522) PubChem (16759982) PubChem (21039619) PubChem (23902994) PubChem (24212165) PubChem (24779611) PubChem (25771704) PubChem (28467795) PubChem (28467804) PubChem (40768273) PubChem (40768275) PubChem (44263337) PubChem (44287287) PubChem (176777031) PubChem (25771696) PubChem (2825567) PubChem (5460333) PubChem (7098656) PubChem (124422945) PubChem (7098655) PubChem (124897370) PubChem (9883423) PubChem (130253860) PubChem (57685079) PubChem (58592165) PubChem (162931383) PubChem (59847734) PubChem (59859263) PubChem (70387126) PubChem (71045972) PubChem (71051776) PubChem (90660571) PubChem (102018286) PubChem (121357601) PubChem (124185417) PubChem (124426478) PubChem (124427142) PubChem (124897034) PubChem (124897035) PubChem (124897369) PubChem (124897371) PubChem (124897618) PubChem (124897619) PubChem (124897620) PubChem (129162599) PubChem (129635497) PubChem (130253852) PubChem (133688130) PubChem (134612755) PubChem (137117762) PubChem (145130042) PubChem (153356004) PubChem (153741516) PubChem (154172615) PubChem (158050161) PubChem (144685586) PubChem (162931384) PubChem (169153737) | |||
| 4 | E, K (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 5 | F, G, H, L, M (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 614 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74855.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2586.4 | |
| All* | Total formula weight | 77442.2 |
