3CAV
Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 5beta-pregnan-3,20-dione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-oxo-5-beta-steroid 4-dehydrogenase | polymer | 326 | 37427.9 | 2 | UniProt (P51857) Pfam (PF00248) | Homo sapiens (Human) | Delta(4)-3-ketosteroid 5-beta-reductase, Aldo-keto reductase family 1 member D1 |
| 2 | C, I (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, J (A, B) | (5BETA)-PREGNANE-3,20-DIONE | non-polymer | 316.5 | 2 | Chemie (CI2) | |||
| 4 | E, K (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 5 | F, G, H, L, M (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 614 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74855.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2586.4 | |
| All* | Total formula weight | 77442.2 |
