3C98

Revised structure of the munc18a-syntaxin1 complex

Replaces:  1DN1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Syntaxin-binding protein 1	polymer	606	69071.2	1	UniProt (P61765) Pfam (PF00995)	Rattus norvegicus (Norway rat)	munc18A, Unc-18 homolog, Unc-18A, Unc-18-1, N- Sec1, rbSec1, p67
2	B (B)	Syntaxin-1A	polymer	279	32451.5	1	UniProt (P32851) Pfam (PF00804) Pfam (PF05739)	Rattus norvegicus (Norway rat)	syntaxin1, Synaptotagmin-associated 35 kDa protein, P35A, Neuron- specific antigen HPC-1
3	C, D (A, B)	water	water		18.0	69	Chemie (HOH)

Sequence modifications

A: 1 - 594 (UniProt: P61765)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 1 - 267 (UniProt: P32851)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101522.7
All*	Total formula weight	101522.7

*Water molecules are not included.