3C7I
X-RAY crystal structure of the complex between the grb2-sh2 domain and a flexible ligand, FPTVN.
Replaces: 2HUYEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Growth factor receptor-bound protein 2 | polymer | 116 | 13687.5 | 1 | UniProt (P62993) Pfam (PF00017) In PDB | Homo sapiens (Human) | Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash |
2 | A | N-{(2R)-4-(methylamino)-4-oxo-2-[4-(phosphonooxy)benzyl]butanoyl}-L-valyl-L-aspartamide | non-polymer | 529.5 | 1 | Chemie (TVN) | |||
3 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
4 | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A: 53 - 162 (UniProt: P62993)
PDB | External Database | Details |
---|---|---|
His 163 | - | expression tag |
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
His 167 | - | expression tag |
His 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13687.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 575.5 | |
All* | Total formula weight | 14263.0 |