3C7I
X-RAY crystal structure of the complex between the grb2-sh2 domain and a flexible ligand, FPTVN.
Replaces: 2HUYFunctional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE TVN A 202 |
| Chain | Residue |
| A | ARG67 |
| A | LEU120 |
| A | TRP121 |
| A | GLU152 |
| A | PRO155 |
| A | HOH214 |
| A | HOH239 |
| A | HOH240 |
| A | HOH272 |
| A | HOH313 |
| A | ARG78 |
| A | ARG86 |
| A | SER88 |
| A | SER90 |
| A | SER96 |
| A | HIS107 |
| A | PHE108 |
| A | LYS109 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A 201 |
| Chain | Residue |
| A | GLN77 |
| A | ARG78 |
| A | HIS79 |
| A | LYS109 |
| A | GLU152 |
| A | HOH206 |
| A | HOH237 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS109 |
