3C6K
Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine
Replaces: 2QFMEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Spermine synthase | polymer | 381 | 43002.9 | 4 | UniProt (P52788) Pfam (PF17950) Pfam (PF17284) Pfam (PF01564) In PDB | Homo sapiens (human) | Spermidine aminopropyltransferase, SPMSY |
2 | A, B, C, D | SPERMIDINE | non-polymer | 145.2 | 4 | Chemie (SPD) | |||
3 | A, B, C, D | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 4 | Chemie (MTA) | |||
4 | water | water | 18.0 | 1164 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 7 - 368 (UniProt: P52788)
PDB | External Database | Details |
---|---|---|
Met -12 | - | expression tag |
Gly -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
Ser -2 | - | expression tag |
Ser -1 | - | expression tag |
Gly 0 | - | expression tag |
Leu 1 | - | expression tag |
Val 2 | - | expression tag |
Pro 3 | - | expression tag |
Arg 4 | - | expression tag |
Gly 5 | - | expression tag |
Ser 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 172011.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1770.3 | |
All* | Total formula weight | 173781.8 |