3C5H

Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Glucocorticoid receptor DNA-binding factor 1	polymer	255	28946.7	1	UniProt (Q9NRY4) Pfam (PF00071)	Homo sapiens (human)	Glucocorticoid receptor repression factor 1, GRF-1, Rho GAP p190A, p190-A
2	B, C (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	D (A)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	1	Chemie (GNP)
4	E, F, G, H, I (A)	UNKNOWN ATOM OR ION	non-polymer			5	Chemie (UNX)
5	J (A)	water	water		18.0	96	Chemie (HOH)

Sequence modifications

A: 13 - 249 (UniProt: Q9NRY4)

PDB	External Database	Details
Met -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Ser 2	-	expression tag
Ser 3	-	expression tag
Gly 4	-	expression tag
Arg 5	-	expression tag
Glu 6	-	expression tag
Asn 7	-	expression tag
Leu 8	-	expression tag
Tyr 9	-	expression tag
Phe 10	-	expression tag
Gln 11	-	expression tag
Gly 12	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28946.7
Non-Polymers*	Number of molecules	8
	Total formula weight	570.8
All*	Total formula weight	29517.5

*Water molecules are not included.