3C3O

ALIX Bro1-domain:CHMIP4A co-crystal structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Programmed cell death 6-interacting protein	polymer	380	42735.8	1	UniProt (Q8WUM4) Pfam (PF03097)	Homo sapiens (Human)	PDCD6-interacting protein, ALG-2-interacting protein 1, Hp95
2	B (B)	Charged multivesicular body protein 4a peptide	polymer	13	1518.6	1	UniProt (Q9BY43)		Chromatin-modifying protein 4a, CHMP4a, Vacuolar protein-sorting-associated protein 7-1, SNF7- 1, hSnf-1, SNF7 homolog associated with Alix-2
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	D, E (A, B)	water	water		18.0	127	Chemie (HOH)

Sequence modifications

A: 1 - 359 (UniProt: Q8WUM4)

PDB	External Database	Details
Met -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Gln -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44254.4
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	44346.5

*Water molecules are not included.