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3C35

Crystal structure of GluR5 ligand-binding core in complex with cesium at 1.97 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1polymer25829253.62UniProt (P22756)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Rat)Glutamate receptor 5, GluR-5, GluR5
2C, D, E, F, G...
(A, B)
CESIUM IONnon-polymer132.913Chemie (CS)
3I
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4J, T
(A, B)
3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINEnon-polymer213.22Chemie (KAI)
5K, L, U
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
6V, W
(A, B)
waterwater18.0400Chemie (HOH)
Sequence modifications
A, B: 3 - 116 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
A, B: 119 - 258 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 117-linker
Thr 118-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58507.1
Non-Polymers*Number of molecules19
Total formula weight2466.0
All*Total formula weight60973.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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