3C10
Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with Trichostatin A (TSA)
Replaces: 2PQPEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone deacetylase 7a | polymer | 423 | 45518.3 | 3 | UniProt (Q8WUI4) Pfam (PF00850) | Homo sapiens (human) | HD7a, HDAC7 |
| 2 | D, E, I, J, N... (A, B, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F, G, K, L, P... (A, B, C) | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 4 | H, M, R (A, B, C) | TRICHOSTATIN A | non-polymer | 302.4 | 3 | Chemie (TSN) | |||
| 5 | S, T, U (A, B, C) | water | water | 18.0 | 459 | Chemie (HOH) |
Sequence modifications
A, B, C: 482 - 903 (UniProt: Q8WUI4)
| PDB | External Database | Details |
|---|---|---|
| Gly 481 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 136555.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1534.1 | |
| All* | Total formula weight | 138089.2 |
