3BV9
Structure of Thrombin Bound to the Inhibitor FM19
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thrombin light chain | polymer | 31 | 3647.1 | 1 | UniProt (P00734) Pfam (PF09396) | ||
| 2 | B (B) | Thrombin heavy chain | polymer | 259 | 29694.1 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (C) | FM19 inhibitor | polymer | 6 | 653.8 | 1 | BIRD (PRD_000276) | ||
| 4 | D, E, F (B) | IODIDE ION | non-polymer | 126.9 | 3 | Chemie (IOD) | |||
| 5 | G (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | H, I (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | J, K, L (A, B, C) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
B: 16 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 77 | Arg 436 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 33995.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 587.9 | |
| All* | Total formula weight | 34582.9 |
