3BUV
Crystal structure of human Delta(4)-3-ketosteroid 5-beta-reductase in complex with NADP and HEPES. Resolution: 1.35 A.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | 3-oxo-5-beta-steroid 4-dehydrogenase | polymer | 326 | 37427.9 | 2 | UniProt (P51857) Pfam (PF00248) | Homo sapiens (human) | Delta(4)-3-ketosteroid 5-beta-reductase, Aldo-keto reductase family 1 member D1 |
| 2 | C, F (B, A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, E (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | G (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | H, I (B, A) | water | water | 18.0 | 556 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74855.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1909.3 | |
| All* | Total formula weight | 76765.1 |
