3BS9
X-ray structure of human TIA-1 RRM2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nucleolysin TIA-1 isoform p40 | polymer | 87 | 9453.7 | 2 | UniProt (P31483) Pfam (PF00076) | Homo sapiens (human) | RNA-binding protein TIA-1, p40-TIA-1 |
| 2 | C, D, E, F, G... (A, B) | IODIDE ION | non-polymer | 126.9 | 7 | Chemie (IOD) | |||
| 3 | J, K (A, B) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A, B: 94 - 175 (UniProt: P31483)
| PDB | External Database | Details |
|---|---|---|
| Gly 89 | - | expression tag |
| Pro 90 | - | expression tag |
| Leu 91 | - | expression tag |
| Gly 92 | - | expression tag |
| Ser 93 | - | expression tag |
| Glu 105 | Gln 116 | SEE REMARK 999 |
| Ala 109 | Glu 120 | engineered mutation |
| Ala 110 | Asp 121 | engineered mutation |
| Ala 112 | Lys 123 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18907.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 888.3 | |
| All* | Total formula weight | 19795.7 |
