3BS9

X-ray structure of human TIA-1 RRM2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Nucleolysin TIA-1 isoform p40	polymer	87	9453.7	2	UniProt (P31483) Pfam (PF00076) In PDB	Homo sapiens (human)	RNA-binding protein TIA-1, p40-TIA-1
2	A, B	IODIDE ION	non-polymer		126.9	7	Chemie (IOD)
3		water	water		18.0	118	Chemie (HOH)

Sequence modifications

A, B: 94 - 175 (UniProt: P31483)

PDB	External Database	Details
Gly 89	-	expression tag
Pro 90	-	expression tag
Leu 91	-	expression tag
Gly 92	-	expression tag
Ser 93	-	expression tag
Glu 105	Gln 116	SEE REMARK 999
Ala 109	Glu 120	engineered mutation
Ala 110	Asp 121	engineered mutation
Ala 112	Lys 123	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	18907.4
Non-Polymers*	Number of molecules	7
	Total formula weight	888.3
All*	Total formula weight	19795.7

*Water molecules are not included.