3BPU
Crystal structure of the 3rd PDZ domain of human membrane associated guanylate kinase, C677S and C709S double mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | polymer | 88 | 9550.0 | 1 | UniProt (Q96QZ7) Pfam (PF00595) | Homo sapiens (human) | BAI1-associated protein 1, BAP-1, Membrane-associated guanylate kinase inverted 1, MAGI-1, Atrophin-1-interacting protein 3, AIP3, WW domain-containing protein 3, WWP3, Trinucleotide repeat-containing gene 19 protein |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A: 640 - 721 (UniProt: Q96QZ7)
| PDB | External Database | Details |
|---|---|---|
| Ser 638 | - | expression tag |
| Met 639 | - | expression tag |
| Ser 677 | Cys 677 | engineered mutation |
| Ser 709 | Cys 709 | engineered mutation |
| Gln 722 | - | expression tag |
| Thr 723 | - | expression tag |
| Arg 724 | - | expression tag |
| Leu 725 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 9550.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 9680.8 |
