3BPT
Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-hydroxyisobutyryl-CoA hydrolase | polymer | 363 | 41078.5 | 1 | UniProt (Q6NVY1) Pfam (PF16113) | Homo sapiens (human) | 3-hydroxyisobutyryl-coenzyme A hydrolase, HIBYL-CoA-H, HIB-CoA hydrolase |
| 2 | B (A) | 3,5,7,3',4'-PENTAHYDROXYFLAVONE | non-polymer | 302.2 | 1 | Chemie (QUE) | |||
| 3 | C (A) | (2R)-3-HYDROXY-2-METHYLPROPANOIC ACID | non-polymer | 104.1 | 1 | Chemie (HIU) | |||
| 4 | D (A) | water | water | 18.0 | 587 | Chemie (HOH) |
Sequence modifications
A: 32 - 386 (UniProt: Q6NVY1)
| PDB | External Database | Details |
|---|---|---|
| Mse 31 | - | expression tag |
| Gly 41 | Glu 41 | conflict |
| Ala 387 | - | expression tag |
| Glu 388 | - | expression tag |
| Asn 389 | - | expression tag |
| Leu 390 | - | expression tag |
| Tyr 391 | - | expression tag |
| Phe 392 | - | expression tag |
| Gln 393 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41078.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 406.3 | |
| All* | Total formula weight | 41484.9 |
