3BPF
Crystal Structure of Falcipain-2 with Its inhibitor, E64
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cysteine protease falcipain-2 | polymer | 241 | 27186.7 | 4 | UniProt (Q9NBD4) Pfam (PF00112) UniProt (by SIFTS) (Q8I6U4) | Plasmodium falciparum | |
| 2 | E, F, G, I (A, B, C, D) | N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | non-polymer | 360.4 | 4 | Chemie (E64) | |||
| 3 | H (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 241 (UniProt: Q9NBD4)
| PDB | External Database | Details |
|---|---|---|
| Gln 171 | Glu 414 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 108746.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1533.8 | |
| All* | Total formula weight | 110280.5 |
