Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE E64 A 242 |
| Chain | Residue |
| A | GLN36 |
| A | LEU172 |
| A | ASN173 |
| A | HIS174 |
| A | GLY40 |
| A | SER41 |
| A | CYS42 |
| A | TRP43 |
| A | TYR78 |
| A | ASN81 |
| A | GLY82 |
| A | GLY83 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE E64 B 242 |
| Chain | Residue |
| B | GLN36 |
| B | GLY40 |
| B | SER41 |
| B | CYS42 |
| B | TRP43 |
| B | ASN81 |
| B | GLY82 |
| B | GLY83 |
| B | ASN173 |
| B | HIS174 |
| D | GLN209 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE E64 C 242 |
| Chain | Residue |
| C | GLN36 |
| C | GLY40 |
| C | SER41 |
| C | CYS42 |
| C | TRP43 |
| C | TYR78 |
| C | ASN81 |
| C | GLY82 |
| C | GLY83 |
| C | SER149 |
| C | ASN173 |
| C | HIS174 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 243 |
| Chain | Residue |
| C | SER130 |
| C | PRO132 |
| C | THR233 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE E64 D 242 |
| Chain | Residue |
| A | GLN209 |
| D | GLN36 |
| D | GLY40 |
| D | SER41 |
| D | CYS42 |
| D | TRP43 |
| D | TYR78 |
| D | ASN81 |
| D | GLY82 |
| D | GLY83 |
| D | LEU84 |
| D | HIS174 |
| D | ALA175 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QKnCGSCWAfSS |
| Chain | Residue | Details |
| A | GLN36-SER47 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. LNHAVMLVGFG |
| Chain | Residue | Details |
| A | LEU172-GLY182 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Nose motif; required for the correct folding of the mature form","evidences":[{"source":"PubMed","id":"11827964","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10088","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10089","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10090","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 18 |
| Details | Motif: {"description":"Arm motif; binds to host hemoglobin and required for the inhibitory interaction between the propeptide and the catalytic domain","evidences":[{"source":"PubMed","id":"15964982","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | ASN204 | |
| A | CYS42 | |
| A | HIS174 | |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | ASN204 | |
| B | HIS174 | |
| B | GLN36 | |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| C | ASN204 | |
| C | HIS174 | |
| C | GLN36 | |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| D | ASN204 | |
| D | HIS174 | |
| D | GLN36 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | ASN204 | |
| B | CYS42 | |
| B | HIS174 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| C | ASN204 | |
| C | CYS42 | |
| C | HIS174 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| D | ASN204 | |
| D | CYS42 | |
| D | HIS174 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | CYS42 | |
| A | HIS174 | |
| A | GLN36 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | CYS42 | |
| B | HIS174 | |
| B | GLN36 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| C | CYS42 | |
| C | HIS174 | |
| C | GLN36 | |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| D | CYS42 | |
| D | HIS174 | |
| D | GLN36 | |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | ASN204 | |
| A | HIS174 | |
| A | GLN36 | |
