3BNZ
Crystal structure of Thymidylate Synthase ternary complex with dUMP and 8A inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthase | polymer | 316 | 36630.5 | 1 | UniProt (P00469) Pfam (PF00303) | Lactobacillus casei | TS, TSase |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (UMP) | |||
| 4 | D (A) | 4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzonitrile | non-polymer | 262.3 | 1 | Chemie (C16) | |||
| 5 | E (A) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36630.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 665.4 | |
| All* | Total formula weight | 37295.9 |
