3BLH
Crystal Structure of Human CDK9/cyclinT1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cell division protein kinase 9 | polymer | 331 | 38054.1 | 1 | UniProt (P50750) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cyclin-dependent kinase 9, Serine/threonine-protein kinase PITALRE, C-2K, Cell division cycle 2-like protein kinase 4 |
| 2 | B | Cyclin-T1 | polymer | 260 | 30119.4 | 1 | UniProt (O60563) Pfam (PF00134) Pfam (PF21797) In PDB | Homo sapiens (Human) | CycT1, Cyclin-T |
| 3 | B | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A: 2 - 330 (UniProt: P50750)
B: 2 - 259 (UniProt: O60563)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Pro 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Pro 1 | - | expression tag |
| Arg 77 | Gln 77 | engineered mutation |
| Gly 96 | Glu 96 | engineered mutation |
| Leu 241 | Phe 241 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68173.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 122.1 | |
| All* | Total formula weight | 68295.7 |
