3BLB

Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alpha-mannosidase 2	polymer	1045	119701.6	1	UniProt (Q24451) Pfam (PF01074) Pfam (PF09261) Pfam (PF21260) Pfam (PF07748) Pfam (PF18230) In PDB	Drosophila melanogaster (fruit fly)	Alpha-mannosidase II, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II
2	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	A	1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL	non-polymer		173.2	1	Chemie (SWA)
5	A	(4R)-2-METHYLPENTANE-2,4-DIOL	non-polymer		118.2	1	Chemie (MRD)
6		water	water		18.0	1068	Chemie (HOH)

Sequence modifications

A: 13 - 1045 (UniProt: Q24451)

PDB	External Database	Details
Arg 1	-	expression tag
Ser 2	-	expression tag
Ser 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Gly 10	-	expression tag
Glu 11	-	expression tag
Phe 12	-	expression tag
Lys 907	Glu 970	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	119701.6
Non-Polymers*	Number of molecules	4
	Total formula weight	578.0
All*	Total formula weight	120279.6

*Water molecules are not included.