3BLB
Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-mannosidase 2 | polymer | 1045 | 119701.6 | 1 | UniProt (Q24451) Pfam (PF01074) Pfam (PF09261) Pfam (PF21260) Pfam (PF07748) Pfam (PF18230) | Drosophila melanogaster (fruit fly) | Alpha-mannosidase II, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II |
| 2 | B (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL | non-polymer | 173.2 | 1 | Chemie (SWA) PubChem (16219982) PubChem (5363) PubChem (24796740) PubChem (51683) PubChem (44306724) PubChem (57320180) PubChem (356987) PubChem (59100074) PubChem (73951928) PubChem (11084361) PubChem (101079106) PubChem (101651938) PubChem (10631049) PubChem (10821094) PubChem (10975968) PubChem (11019343) PubChem (11062890) PubChem (11217526) PubChem (13373084) PubChem (13373087) PubChem (13373088) PubChem (126968972) PubChem (130889391) PubChem (147588303) PubChem (162927211) PubChem (163569189) | |||
| 5 | E (A) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) PubChem (7870) PubChem (5288834) PubChem (5288845) | |||
| 6 | F (A) | water | water | 18.0 | 1068 | Chemie (HOH) |
Sequence modifications
A: 13 - 1045 (UniProt: Q24451)
| PDB | External Database | Details |
|---|---|---|
| Arg 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Ser 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Glu 11 | - | expression tag |
| Phe 12 | - | expression tag |
| Lys 907 | Glu 970 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 119701.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 578.0 | |
| All* | Total formula weight | 120279.6 |
