3BKI

Crystal Structure of the GluR2 ligand binding core (S1S2J) in complex with FQX at 1.87 Angstroms

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (P, B, C, D)	Glutamate receptor 2	polymer	263	29221.7	4	UniProt (P19491) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (rat)	GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2
2	E, F, G, H (P, B, C, D)	[1,2,5]oxadiazolo[3,4-g]quinoxaline-6,7(5H,8H)-dione 1-oxide	non-polymer		220.1	4	Chemie (FQX)
3	I, J, K, L (P, B, C, D)	water	water		18.0	855	Chemie (HOH)

Sequence modifications

P, B, C, D: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Gly 1	-	expression tag
Ala 2	-	expression tag

P, B, C, D: 120 - 263 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	116886.7
Non-Polymers*	Number of molecules	4
	Total formula weight	880.6
All*	Total formula weight	117767.3

*Water molecules are not included.